British Air Force Typhoon jets have operated alongside French aircraft in a coordinated attack targeting an subterranean weapons facility in Syria operated by the Daesh militant organization, according to the UK's MoD.
The site, located using intelligence, was thought to be containing munitions and bombs, the release indicated, and was located in hills just above the ancient city of Palmyra in the heart of Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to strike a number of access tunnels leading to the facility... preliminary assessments indicate the target was engaged successfully," the ministry announced.
There was no indication of any civilian casualties in the strike late on Saturday and every plane involved returned to base without incident, the defence officials confirmed.
The British jets were assisted by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced militant control over large swathes of Syria and Iraq prior to its 2019 collapse.
"This action demonstrates the UK's leading role, and commitment to stand shoulder to shoulder with allied nations, to eradicate any revival of Daesh and their dangerous and violent ideologies in the region," Britain's Defence Chief John Healey remarked.
RAF aircraft have carried out surveillance missions over Syria to "forestall any efforts to regroup" of Islamic State subsequent to its military defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank the personnel of the UK armed forces involved in this strike for their expertise and their bravery," Healey added. "They were part of a great many British personnel deployed over the holidays. This action, to eliminate militants who endanger our security, highlights how UK forces are prepared to act, throughout the year, ensuring Britain's security domestically and strong abroad."
In December, the US military carried out what it called a "massive strike" on IS targets in the country, subsequent to an attack killed two US troops and a local interpreter in Palmyra.
The U.N. says Islamic State still boasts between 5,000 and 7,000 fighters in both countries.